CLINICAI STUDY OF THE LEVEL OF SERUM VITAMIN A AND THE CELLULAR IMMUNE FUNCTION IN CHILDREN WITH MEASLES

Liu QB

Children’s Hospital, Chongqing University of Medical Sciences Chongqing, China

 

Objective: To explore the relation between vitamin A and the cellular immune function in children with measles.

Methods: Serum Vitamin A test, PPD test, and lymphocyte subsets assay were performed in 30 inpatients with measles, compared with 20 healthy children at the same time.

Results: (1). The levels of serum vitamin A were remarkably decreased in 30 patients (p<0.001) (2). All PPD tests of patients were negative (p<0.005) (3). The levels of CD3 and CD4 were remarkably decreased (all p<0.01), the level of CD8 was remarkably increased (p<0.001) and CD4/CD8 was remarkably decreased (p<0.001) in patients.(4).The levels of CD3 ,CD4 or CD8 were different, or weren't entirely same in patients with different levels of serum vitamin A (all p<0.01)

Conclusion: The levels of serum vitamin A are remarkably decreased in children with measles. There is a close relation between vitamin A deficency and cellular immunity.

 

 

 
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