CLINICAI STUDY OF THE
LEVEL OF SERUM VITAMIN A AND THE CELLULAR IMMUNE FUNCTION IN CHILDREN WITH
MEASLES
Liu QB
Children’s Hospital, Chongqing University of Medical Sciences
Chongqing, China
Objective: To
explore the relation between vitamin A and the cellular immune function in
children with measles.
Methods:
Serum Vitamin A test, PPD test, and lymphocyte subsets assay were performed
in 30 inpatients with measles, compared with 20 healthy children at the
same time.
Results: (1).
The levels of serum vitamin A were remarkably decreased in 30 patients (p<0.001) (2). All PPD tests of
patients were negative (p<0.005)
(3). The levels of CD3 and CD4 were remarkably
decreased (all p<0.01), the
level of CD8 was remarkably increased (p<0.001)
and CD4/CD8 was remarkably decreased (p<0.001) in patients.(4).The
levels of CD3 ,CD4 or CD8 were different,
or weren't entirely same in patients with different levels of serum vitamin
A (all p<0.01)
Conclusion:
The levels of serum vitamin A are remarkably decreased in children with
measles. There is a close relation between vitamin A deficency and cellular
immunity.