CURATIVE EFFECT TO HIGH FEVER IN CHILDREN BY INTRAVENOUS
XINGNAOJING INFUSION
Jia H-Q, Yu J-L
Children’s Hospital, Chongqing Medical
College, Chongqing, China
Objective: To investigate the curative effect to high fever in children by
Xingnaojing injection---a kind of preparation of Chinese traditional
medicine consisted of muskiness, borneol, gardenia and tulip.
Methods: Clinic trial as follows: From Apr. to June 1998,
77 children with high fever (axilla temperature﹥39℃) in outpatient department were randomly divided into two groups.
The distribution of age between the treatment group and control group was
not different statistically. The distribution of diseases was 43 cases of
acute upper respiratory infection, 8 cases of purulent tonsillitis, 2 cases
of bronchitis, 1 case of pneumonia and 1 case of diarrhea in treatment
group, while 17, 4, 1, 0, 0,respectively, in control group. The Xingnaojing
injection 0.4~0.6ml/kg.d adding into 10% glucose fluid 100 ml was intravenously
infused in treatment group, while the other group didn’t used this
injection. Antibiotics were used in both groups. The temperatures were
taken after beginning of transfusion 1, 2, 3 and 4 hours. At the same time,
the specially observing of rash and convulsion were made. Efficacious
outcome was defined if the patient’s high temperature became normal.
Results: The effective rate in the treatment group 58.2%(32/55), with 2 cases(3.6%)in
one hour, 15 cases(27.3%)in two hours and 31 cases (56.4%)in three hours
defervesced. But only 7 cases of 22(31.8%)defervesced in 4 hours. Significant
difference (χ2=4.387,P﹤0.05) existed in the two groups. Six of 8
infants suffering from purulent tonsillitis, temperatures fell to normal
during 4 hours’ Xingnaojing infusion. But all 4 cases of purulent
tonsillitis were not defervesced in 4 hours.The rash and convulsion didn’t
appeared in both groups.
Conclusion: Intravenous Xingnaojing infusion is effective and
safe for controlling children’s symptom of high fever.
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