THE LEVELS OF SERUM D-DIMER IN CHILDREN WITH
HENOCH-SCHONLEIN PURPURA
Tang Xuemei, Li Yongbai, Wu Daoqi, et
al.
Children
Hospital, Chongqing University of Medical Sciences, China
Objective:
To observe the levels of serum D-Dimer and to investigate the relationship
between serum D-Dimer in children with Henoch-Schonlein Purpura (HSP) and
pathological damages and outcome.
Methods:
Thirty-four children with HSP were devided into two groups depending on
whether there is clinical manifestation of renal damage. Serum D-Dimer in
all cases with HSP were measured by ELISA.
Results:
The serum levels of D-Dimer all cases with HSP were higher than those of
health controls obviously (P<0.05). However, no significant difference
was found in the levels of two patient groups (P>0.05).
Conclusions:
Incase of hypercoagulable state, D-Dimer could be a good prameter
clinically, but not a believeable measurement to distinguish cases with
renal damage. Moreover, D-Dimer could be used to evaluate the efficiency of
resisting hypercoagulability therapy.
Key
Words: Serum D-Dimer, Children, Henoch-Schonlein Purpura, Renal damage,
Hypercoagulable state, Resisting hypercoagulability