CONJUNCTIVITIS CAUSED BY CHLAMYDIA TRACHOMATIS IN NEONATES

Wu Shixiao, Yang Jun, Wei Hong, et al.

Children¡¯s Hospital, Chongqing, China

 

Objective: To Investigate The Prevalence Of Neonatal Conjunctivitis caused by Chlamydia trachomatis (CT) and to evaluate 2 methods of detecting CT in neonatal conjunctivitis.

Methods: A total of 125 conjunctival scrapings taken from neonates with conjunctivitis in Children¡¯s Hospital from 1997 to 1998 was tested by the McCoy cell culture and polymerase chain reaction (PCR).

Results: The detection rates of CT in neonatal conjunctivitis were 41.6% by cell culture and 51.2% by PCR. The sensitivities of cell culture and PCR were 81.3% and 94.2%,respectively. The prevalence of CT con-junctivitis was obviously higher in neonates delivered through vagina than those by cesarean section delivery (74% and 9%,respectively, P<0.01).

Conclusion: CT was the main pathogenic microorganism of neonatal conjunctivitis in Children¡¯s Hospital from 1997 to 1998(51.2%). PCR was more sensitive than the cell culture in the detection of CT.

 

 
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