ASSESSMENT OF AUTONOMIC FUNCTION BY ANALYSIS
OF HEART RATE VARIABILITY IN CHILDREN WITH
HYPERTHYROIDISM
1Jiang
DQ, 2Yu G-S, 2Tian
J, 2Qian Y-R, 2Zhong J-R, 2Chen Y
The
Fourth People’s Hospital of Zigong, Zigong, China
Children’s
Hospital, Chongqing, China
Objective:
The aim of the present study was both to assessment autonomic nervous
system (ANS) function in patients with hyperthyroidism by the heart rate
variability (HRV) and to analysis the impact of hyperthyroidism on the
cardiovascular
Methods:
Indexes of HRV were measured in 13 hyperthyroidism and 26 healthy controls.
Time domain indexes and Spectral indexes of HRV were derived.
Results:
1. There was significance increase both HFUN% and LF/HF
comparing with
hyperthyroidism and the
control group over a 24-hour period. 2. In patients with control group, there were significance
increases in the indexes of LFUN and LF/HF ratio during waking
hours, whereas both
HFUN and HF bands were significance increase during sleeping
hour. In patients with hyperthyroidism, there were no significance differences in all spectral indexes of HRV. 3. There were
significance differences in patients
with hyperthyroidism in any time domain indexes of HRV comparing with control
group over a 24-hour period. In hyperthyroidism group, the night-day difference in HRV was significance
smaller comparing with control
group.
Conclusion:
In patients with hyperthyroidism an autonomic imbalance, thyroid
hormone excess may determine reduced parasympathetic activity and, thus, a
relative hyper sympathetic tone. It will be important to adjust the
abnormal cardiac autonomic activity promptly.