1P-S2-2

LIMITATIONS AND COMPLICATIONS OF INTERVENTIONAL CATHETERIZATION

Toshio Nakanishi

Pediatric Cardiology, Heart Institute of Japan, Tokyo Women’s Medical University, Tokyo Japan

 

During the last 30 years, a number of devices have been developed for transcatheter occlusion of patent ductus arteriosus (PDA) and atrial septal defect (ASD) and have been greeted with enthusiasm initially and a varying degree of disappointment afterwards. Although the Amplatzer occluder is increasingly used for ASD closure, surgical closure is still the standard treatment and we need to see the long-term results. Excellent results have been obtained with coils for the closure of a small PDA, but major complications, including hemolysis, can occur in 1%. After balloon dilation of coarctation, aneurysm is observed in about 5% and restenosis in 20 -30%. Mild stenosis may remain and upper body hypertension may persist, especially during excercise.  Stent placement may solve some of the problems of balloon dilation, but the stents currently available are not perfect for implantation in the aorta. Restenosis and aortic regurgitation are common long after balloon dilation of the aortic valve, and balloon dilation should be considered to be a palliative therapy. The success rate of balloon dilation of pulmonary artery stenosis is low (60-80%), and restenosis is common (about 20%).  Stent placement in the branch pulmonary artery usually results in good relief of stenosis, but the pulmonary artery with the stent does not grow. Major complications including death during interventional catheterization occur in 1-2%. Further progress is necessary to overcome these limitations and decrease complications of interventional catheterization in infants and children.