USING INSTENON FOR CHILDREN WITH BURNS, COMPLICATED WITH ENCEPHALOPATHY

Djumabekov TA, Nurmagambetova BK, Gurkabaeva BD, Zikeyeva AV, Aitmagambetova SR

Children’s Hospital №1, Almaty, Republic of Kazakhstan

Objectives: To determine efficiency of a medicine Instenon, improving metabolic processes in a central nervous system for patients with a burn trauma complicated with encephalopathy of hypoxic and toxic henesis.

Methods: 34 children at the age from 6 months to 14 years were involved in examination. The area of an injury varied from 10% to 62%. Consciousness disturbances of a different damage rate were observed for 26 children with encephalopathy. 4 children were in coma of I-II degree, another 4 ones had II-III degree of it and were transferred to the artificial lung. All children had wide and fine tremor upper and inferior limbs, also chin tremor and possibility of spasmotic syndrome. Together with antishock therapy Instenon was prescribed intravenously, 1 time per day with 5% glucosa solution: children younger 1 year - 1 ml/day, children elder 1 year - 2 ml/day.

Results: Functions of the central nervous system were quickly recovered. Consciousness was recovered with coma recovery for 2-3 days. The spontaneous breathing and function of cardiovascular system were recovered quickly.

Conclusion: Using Instenon in treatment of patients with burns complicated with encephalopathy, provided of a general condition improvement and also critical condition recovery on 2 day. In the result of this lethality was lowered, staying patients in clinic was reduced by 3 days. That allows to use Instenon widely for that patients treatment.

2020