COMPARATION OD RATE SENSITIVITY AND SPECIFICITY BETWEEN SMEAR EXAMINATION AND FLUORESCENCE MICROSCOPY IN DIAGNOSIS OF PULMONARY TUBERSULOSIS

Simonovska LJ1, Nanovic Z1, Trajcevska M1, Galev A2

1 Institute for Lung Diseases and Tuberculosis

2 International organization of migration, Skopje, Macedonia

 

Objective: The aim of this study was to determinate and to compare the rate of sensitivity and specificity between smear examination and fluorescence microscopy.

Methods: Smear examination and fluorescence microscopy was performed from the same specimen of sputum in two groups of patients. Group A consisted of 37 patients with active pulmonary tuberculosis and group B consisted of 42 patients with different non-tuberculosis pulmonary diseases.

Results: For smear examination we found sensitivity rate of 18.92%, specificity rate of 100%, predictive value of positive results in 100% and predictive value of negative results in 58.33%. For fluorescence microscopy we found sensitivity rate of 46%, specificity rate of 88.1%. Predictive value of positive results was 77.27% and predictive value of negative results was 64.9%. With Chi-Square test we found statistically significant difference p< 0.001 in the rates of sensitivity and specificity between smear examination and fluorescence microscopy.

Conclusion: Smear examination with fluorescence microscopy is a useful additional tool for diagnosis of pulmonary tuberculosis.

 
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