COMPARATION OD RATE
SENSITIVITY AND SPECIFICITY BETWEEN SMEAR EXAMINATION AND FLUORESCENCE
MICROSCOPY IN DIAGNOSIS OF PULMONARY TUBERSULOSIS
Simonovska
LJ1, Nanovic Z1, Trajcevska M1, Galev A2
1
Institute for Lung Diseases and Tuberculosis
2
International organization of migration, Skopje, Macedonia
Objective: The aim of this study
was to determinate and to compare the rate of sensitivity and specificity
between smear examination and fluorescence microscopy.
Methods: Smear examination and
fluorescence microscopy was performed from the same specimen of sputum in
two groups of patients. Group A consisted of 37 patients with active
pulmonary tuberculosis and group B consisted of 42 patients with different
non-tuberculosis pulmonary diseases.
Results: For smear examination
we found sensitivity rate of 18.92%, specificity rate of 100%, predictive
value of positive results in 100% and predictive value of negative results
in 58.33%. For fluorescence microscopy we found sensitivity rate of 46%,
specificity rate of 88.1%. Predictive value of positive results was 77.27%
and predictive value of negative results was 64.9%. With Chi-Square test we
found statistically significant difference p< 0.001 in the rates of
sensitivity and specificity between smear examination and fluorescence
microscopy.
Conclusion: Smear examination with
fluorescence microscopy is a useful additional tool for diagnosis of
pulmonary tuberculosis.