PULMONARY
FUNCTIONAL TESTINGS IN CHILDREN WITH CYSTIC FIBROSIS
Seckova L1, Hristova M1, Nikolovski LJ1, Fustic S1, Vlaski E1,
Trajcevska M2
1 University Children Hospital, Skopje, Macedonia
2 Institute for lung diseases and tuberculosis, Skopje, Macedonia
Objective: Chronic respiratory tract infection is
important contributor to the loss of the lung function in the patients with
cystic fibrosis (CF). The aim was to discover the differences in pulmonary
functional testing in those patients.
Methods: We examined 22 children with CF (divided in
three groups: children with continuously colonization with P.aeruginosa
40,9%; children without any bacteriological findings in sputum 45,4% and
those with temporary findings P.eruginosa 13,6%). Lung functional testing
was made by FLOW screen pro (analyzing FEV1, FVC, MEF50, MEF35).
Results: Statistical analysis of variance and multiple
range test. The data showed statistically differences p< 0.04 between
children without any bacteriological finding and those who have
continuously colonization with P.aeruginosa in parameter FEV1.
Conclusion: Colonization with P.aeruginosa in
children with CF is accompanied with abnormality in lung functional testing
especially in FEV1.