THE OBSERVATION OF EFFECTIVENESS OF PULMICORT REPULES ON THE ACUTE
ATTACK OF ASTHMA IN CHILDREN
Kang Xiaohui, Liu Yanxia, Chen Zaili, Chen Yuzhi
The Capital Institute of Pediatrics
Objective: To evaluate the effectiveness of
Pulmicort Repules on the Acute Attack of Asthma in children.
Method: 70 patients were randomizedly divided into
three groups. In the test group, 30 patients received Pulmicort Repules,
Ventolin and Atrovent by nebulisation. In the two control groups, group I,
composed of 20 patients, received Ventolin and Atroven by nebulisation and
Dexamethasone by injection, and group II, also composed of 20 patients,
received Dexamethasone by injection only. Symptoms (dyspnea, cough,
wheezing) and sign (wheezing) were observed before and after treatment, and
times of symptoms and sign disappearance were compared.
Result: The improved scales of symptoms and signs were
observed in one hour after treatment and showed that the test group gained
better therapeutic effectiveness than control group I. The improved scale
of test group are dyspnea 1.05; cough 1.1; wheezing (symptom) 1.4; and
wheezing (sign) 1.4. The
scales for control group I are 0.88; 0.68; 0.98, 0.85, respectively. The
difference is significant between the two groups (p<0.05). The time of
symptom and sign disappearance in the test group was shorter than in the
control groups (p<0.05). The times (days) for dyspnea, cough, wheezing
(symptom) and wheezing (sign) disappearance are as follows: test group
times are 1.87, 4.13, 3.0, 3.6, respectively; control group I times are:
3.9, 8.0, 5.8, 8.0, respectively; and control group II times are 4.1, 8.9,
6.6, 7.1, respectively.
Conclusion: Pulmicort Repules is a more effective
medication for the acute attack of Asthma in children than Dexamethasone by
injection and Ventolin and
Atrovent by nebulisation.
Key Words: Pulmicort
Repules, Corticosteroid, Asthma, Children