THE OBSERVATION OF EFFECTIVENESS OF PULMICORT REPULES ON THE ACUTE ATTACK OF ASTHMA IN CHILDREN

Kang Xiaohui, Liu Yanxia, Chen Zaili, Chen Yuzhi

The Capital Institute of Pediatrics

 

Objective: To evaluate the effectiveness of Pulmicort Repules on the Acute Attack of Asthma in children.

Method: 70 patients were randomizedly divided into three groups. In the test group, 30 patients received Pulmicort Repules, Ventolin and Atrovent by nebulisation. In the two control groups, group I, composed of 20 patients, received Ventolin and Atroven by nebulisation and Dexamethasone by injection, and group II, also composed of 20 patients, received Dexamethasone by injection only. Symptoms (dyspnea, cough, wheezing) and sign (wheezing) were observed before and after treatment, and times of symptoms and sign disappearance were compared.

Result: The improved scales of symptoms and signs were observed in one hour after treatment and showed that the test group gained better therapeutic effectiveness than control group I. The improved scale of test group are dyspnea 1.05; cough 1.1; wheezing (symptom) 1.4; and wheezing (sign)  1.4. The scales for control group I are 0.88; 0.68; 0.98, 0.85, respectively. The difference is significant between the two groups (p<0.05). The time of symptom and sign disappearance in the test group was shorter than in the control groups (p<0.05). The times (days) for dyspnea, cough, wheezing (symptom) and wheezing (sign) disappearance are as follows: test group times are 1.87, 4.13, 3.0, 3.6, respectively; control group I times are: 3.9, 8.0, 5.8, 8.0, respectively; and control group II times are 4.1, 8.9, 6.6, 7.1, respectively.

Conclusion: Pulmicort Repules is a more effective medication for the acute attack of Asthma in children than Dexamethasone by injection and  Ventolin and Atrovent by nebulisation.

 

Key Words: Pulmicort Repules, Corticosteroid, Asthma, Children

 
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