GROWTH DEVELOPMENT IN
IDIOPATHIC APLASTIC – ANEMIA GIRL AFTER TREATED WITH GM – CSF (CASE REPORT)
Bidasari Lubis
Department
Of Pediatric – H. Adam Malik Hospital, Medical School, North Sumatera
University - Medan
GM – CSF is glycoprotein
that influence the proliferation, differentiation, maturation and
activation of hemopoetic cells, especially effects on granulocytes and
macrophages / menocytes and will promote the proliferation of erythroid and
megakaryocytic progenitor. We report a girl, 7th years old with
diagnosed Idiopathic Aplastic Anemia had not responded to corticosteroid
and has been apparently successfully treated with GM – CSF (*Leucomax) at
dosage 3 ug/kg/day/sc and increased gradually every 4 days till maximum 5
ug/kg/day/sc for 28th days. After 3 years 6 months evaluation,
she had not required any further blood transfusion and growth development
was still normal range.