TOTAL REGRESSION OF MULTIPLE BRAIN ABSCESSES IN NEWBORN
FOLLOWING CONSERVATIVE TREATMENT
Furmaga-Jablonska W, Szponar E, Billewicz-Kraczkowska A
Department of Paediatrics, Medical University School of Lublin,
Poland
Objective: A preterm infant born at the 34th
week of pregnancy with birth weight 1890g, with jaundice, pneumonia and
anemia has been described. In the NICU perinatal sepsis (Staphylococcus
epidermidis methycylin-resistant) was diagnosed, treated with Vancocin and
Meronem. Routine USG of CNS
done on the twenty first day of life and then CT-scan of the head proved
the presence of two multiple cerebral abscesses with the tendency to encephlomalacia as well as to
creation of multiple abscesses. Inflammable character in the cerebro-spinal
fluid was noticed. The bacterial smear of cerebro-spinal fluid was
negative.
Methods: The therapy included Cephotaxime (Claforan) at
the dose 300mg/kg of body weight and Biodacin at the dose of 15 mg/kg of
body weight.
Results: The 3-weeks treatment resulted in achieving the
normalisation of pleocytosis in the cerebro-spinal fluid and the CT-scan of
the head confirmed regression of the previously described changes. The
infant was discharged at the age of 4 months in overall good condition with
no neurologic loses and developmental defects. Presently the physical and
psychomotor development of the child at the age of 14 months is within
normal ranges.
Conclusions: Application of Cephotaxime doses of 300
mg / kg / 24 hours in bacterial meningitis and brain abscesses in premature
newborns provides a chance for total recovery and a correct development of
the treated infants.