ENCEPHALOPATHIC SCORE AS NEURODEVELOPMENT SEQUELAE PREDICTOR IN THE
FIRST 5 YEARS OF LIFE
Fernando Dominguez, Maria del Carmen Roca, Alexis GonzalezEnzo
Duenas
¡°Gonzalez Coro¡± Hospital, Havana, Cuba
Objective: To know the accuracy of an Encephalopathic
Score to predict Neurodeveloment sequelae in first 5 years of life in full
term neonates with Hypoxic Ischemic Encephalopathy.
Material and methods: We have been following
70 full terms neonates discharge from the NICU at ¡°Gonz¨¢lez Coro¡± Hospital
in Havana, Cuba, during their first 5 years of life. Each of them were
evaluated at the end of the first week of life with an Encephalopathic
Score (range 0 to 10) and during the following up study their were
classified as normal, with mild or moderate and severe Neurodevelopmental
alterations. Initial score and outcome were correlated by Kappa Statistical
Index and sensitivity, specificity, positive and negative predictive
values, and efficacy were also calculated.
Results:
Substantial correlation was found between the Encephalopathic Score and the
neurodevelopmental outcome: Kappa = 0.63 ASE 1 = 0.11484 Val/ASE = 7.1. Other results were: Sensitivity 100%, specificity
92%, positive predictive value 62% negative predictive value 100% and
efficacy 93%.
Conclusions:
Encephalopathic Score had good accuracy to predict Neurodevelopmental
disturbances in first 5 years of life because of this method resulted
sensible, specific and effective. We recommend it as a good sequeale
predictor in neonates with Hypoxic Ischemic Encephalopathy not only for
prognosis but also to identify those neonates who must have priority to be
included in Neurodevelopment following up studies.