Text Box: CLINICAL OBSERVATION IN THE TREATMENT OF NEONATAL HYPERBILIRUBINEMIA WITH COMBINING CLOSTRIDIUM BUTYNCUM MIYAIRI WITH SIMOTANG ORAL LIQUID Meng Pu, Zhou Dongfeng, Zhao Ping, et al Department of Pediatrics, Union Hospital of Tongji Medical College, Huazhong Science and Technology University, Wuhan, China Objective: To prevent brain injury caused by bilirubin, neonatal hyperbilirubinemia must be redressed early and effectively. Methods: Clostridium butyricum miyairi and simotang oral liquid were administered together with conventional treatment. Results: Bilirubin level of treatment group (121cases)decreased by a average of (51.09 ¡À25.32)µmol/L a day, which was obviously higher than that of control group (61 cases) [(36.97¡À21.43) µmol/L]. Conclusion: With clostridium butyricum miyairi and simotang oral liquid treating neonatal jaundice, serum bilirubin level could be lowered rapidly and treatment time could be shortened obviously. 2383