NEUROCYSTICERCOSIS ¨C AN E.S.I EXPERIENCE

Swapna K1, Mathur YC2

1 E.S.I. Hospital, Hyderabad, India

2 C.D.R. Hospital, Hyderbad, India

 

Objective:    To study the clinical features, pathology, pathogenesis, EEG and Radiological Findings and Management of Neurocysticercosis.

Methods:     Sixty-three cases with seizure disorders from age 3-12 yrs, brought to Pediatric OPD / hospitalized at E.S.I Hospital, Hyderabad from 6/1990 to 7/1999 were studied.  Children fulfilling the criteria of febrile seizures were excluded from the study group.  All cases were subjected to detailed clinical examination, routine stool, urine, complete blood picture, mantoux test, radiology of chest, skull, serology for Taenia solium antibodies, EEG and C.T. scan Brain.

Results:       The incidence of infectionwith Taenia Solium was found to be 16 cases (25 ¨C 39%) out of 63 studied.  Nine cases (56.2%) presented with generalized seizures.  EEG was abnormal in 6 cases (37.5%) slow wave pattern or spikes were seen.  C.T. Scan Brain. Findings showed Single (62.5%) or multiple (37.5%) ring-enhancing lesions and with perilesional oedema in 6 cases (37.5%).  Serology for T. Solium antibodies was done for all 63 cases.  Serology was positive for 16 cases (25-39%).

Conclusion:  The incidence of Neurocysticercosis in this study was found to be 25 ¨C 39%.  Most cases presented with seizure disorders.  Serological tests. EEG and C.T. scan Brain is helpful in diagnosis.  Ellisa shows presence of antibodies against Taenia Solium antigen in serum, EEG shows slow and spike activity and C.T. Scan Brain shows ring enhancing lesions and calcifications.  Albendazole is the treatment of choice.

 
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