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CLINICAL ANALYSIS OF 79 CHILDREN WITH LYMPHOMA

Xian Y, Xu YH

Children’s Hospital, Chongqing University of Medical Sciences, Chongqing , China

Objective: Since 1989, about 79 children with lymphoma have been hospitalized in our hospital. By studying those cases, we can share our experience with others and use it for the future work on the diagnosis and differential diagnosis of lymphoma.

Methods: Seventy-nine children with lymphoma treated in Children’ Hospital from February 1989 to January 2000 were enrolled in this study. Patient characteristics have been summarized and analyzed using literature describing and statistic analysis.

Results: The number of male patients was bigger than that of female. Most cases occurred in those children with 5-10 years old. The incidence of Non-Hodgkin’s lymphoma(NHL) was higher than that of Hodgkin’s disease (HD). For HD, lymph nodes around neck were the primary first sign and developed slowly. Few other sites of the body were involved at the beginning. Most cases were in stage Ⅰ. For NHL, lymph nodes also were the primary sites involved at the beginning, but most of them were in deep sites such as celiac cavity and mediastina. There were about 15.4% of the other sites involved as the primary first sign at the onset of the disease. Most of the cases were acute, developed rapidly and metastases around easily. Thus most of the cases were in stage Ⅲto Ⅳ clinically.

Conclusion: HD and NHL in children have different clinical characteristics, such as the gender, the incidence, the onset symptom and sign, the disease stage and their development.