2623

CLINICAL AND LABORATORY PECULIARITIES OF THE PERINATAL SEPSIS WITH COMBINED ETHIOLOGY OF THE PREMATURE BORN INFANTS

D. K. Mukhamedjanova, M. M. Azimdjanova

Scientific Research Institute of Pediatrics Tashkent, Uzbekistan

The aim of our research was to work out the criterias of perinatal sepsis’ diagnostics of the bacterial and fungus ethiology of premature born infants.

Under our observation there were 60 premature, infants with sepsis and their mothers. The bacteriologic researches include tests of the female genital discharge, amniotic fluid, the blood from umbilical cord, culture from the oral cavity, blood culture, fecal culture, culture of a wound of the umbilical cord, eyes and skin. Immunological tests: serum lg G.M. A by manchini method, T-B-lymphocytes.

The health status of all infants at the time of admission was severe or even extremely severe. The leading symptom of the sepsis of the combined ethiology was marked with intoxication. The skin was pale with marble shade. We find out the affects of skin in form of dermatitis, eyes as purulent conjunctivitis, oral cavity as stomatitis. The more frequent vomiting, meteorism, clear venous net of the anterior abdominal walls, diarea of green colour with admixture of mucus. It was noted that central nervous system disturbance as excitement or oppression, the increase of the sindrom of hypertension. 83.6% of mothers being ill with toxemia of pregnancy, chronic pyelonephritis, mycotic colpitis, early rupture of amniotic fluid sac, placental separation, cesarean section.

Bacteriologic test of infants showed the following: straureus-30.3%, yeast-like fungi-38.8%, gramm-negative flora in combination with the figure candida genus-30.9% of cases.

The microflora of infants according to specific composition was indentical to their mothers. lmmunologic study demonstrated low level of lgG, T-B-lymphocytes, high levels of lg M and A.