2629

THE CHILDREN IDIOPATHIC SMALL VESSEL VASCULITIS AND RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS

Liu Xiaorong, Shen Ying, Li Yunjuan, et al

Department of Nephrology Beijing Children’s Hospital, Capital University of Medical Sciences, Beijing, China

Objective: We analyzed the clinical and Pathological characteristics of One Patient with idiopathic RPGN and ANCA-related vasculitis.

Methods: Clinical and pathological data from the Patient with idiopathic rapidly progressive glomerulonephritis and ANCA-related Vasculitis was collected and further analyzed.

Results: One patient with idiopathic RPGN was positive for anti-Neutrophil cytoplasmic autoantibodies (ANCA), She showed P-ANCA by indirect immunofluorescence technique. She had fever, Weightloss, anemia, caugh and hemoptysis. The Patient had a positive CRP, and accelerated ESR (≥150mm/h), Typical Pathological findings were diffuse crescents formation. The renal functions of the patient was obviously improved by immunosuppressive therapy.

Conclusion: The results suggested that the Children primary Vasculitis is one of Courses of RPGN.