2631

WBSE AND SAOA LEVELS IN CHILDREN WITH IDIOPATHIC NEPHROTIC SYNDROM

Wang Limin1, Guo Fanli2

1 Department of Pediatrics. The First Affiliated Hospital of Jiamusi University, Jiamusi, China

2 Department of Pediatrics, The Hospital of Heli Forestry Workers

 

Objective: To study changes in the whole blood selenium (WBSE) and serum antioxidation (SAOA) levels in idiopathic nephrotic.

Methods: The serum AOA and whole blood selenium levels were measured in 60 patients with idiopathic nephrotic syndrome aged from two to thirteen years. The serum AOA was determined by TBA method and the whole blood selenium, by fluorophotometry.

Results: The results showed that the serum AOA and whole blood selenium of 60 patients with INS were much lower than those of the controls (p<01.01).

Conclusion: All above results suggested this disease the imbalance between oxidation and antioxidation, and the poor selenium nutrition levels in the disease. Also our study may provide theoretic basis for antioxidant drugs to treat INS.