2658

ORAL GLUCOSE AND PACIFIER REDUCE INSERTION PAIN OF PERIPHERAL INTRAVENOUS CANNULATION IN NEWBORNS

Zhao MH, Zhang YX, Zhang L

The Children’s Hospital of Fudan University, Shanghai, China

Objective: To measure pain symptoms in hospitalized fullterm newborns undergoing routine intravenous infusion via a cannulae placed in peripheral vein of the hand with and without 30% oral glucose (dilute 50% glucose solution with sterilized water) and pacifier (nonnutritive sucking).

Methods: We compared the effects of 30% oral glucose with that of pacifiers and free treatment in a randomized controlled trial in 60 hospitalized fullterm newborns requiring peripheral intravenous cannulation (PIC). Pain was assessed from the Premature Infant Pain Profile (PIPP).

Results: The PIPP score was significantly lower in the group that received 30% oral glucose than the group with pacifier. The PIPP score was also significantly lower in the group with pacifier than the group without any method. The PIPP score in the group without any method indicated that newborns got the nearly moderate pain during PIC procedure.

Conclusions: Our results strongly suggest that 1 ml of a 30% glucose solution given orally before and during insertion reduces the pain significantly and pacifier also reduces the pain but it has the less effect compared with 30% glucose solution. Those methods are easy and reliable to reduce the nearly moderate pain caused by the most common invasive procedure-PIC in fullterm newborns.