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LOW RISK OF CONVULSION RECURRENCE AFTER EARLY WITHDRAWAL OF ANTICONVULSIVE TREATMENT IN THE NEONATAL PERIOD

Zhang Jinhua, Gan Mei

Department of Pediatrics, the First People Hospital, Yulin, Guangxi, China

Objective: To evaluate the risk of convulsion recurrence with the first year of life in infants with neonatal convulsion after early withdrawal of anticonvulsive treatment in the neonatal period.

Methods: 59 convulsive neonates with hypoxic ischemic encephalopathy (HIE) received anticonvulsive treatment with a combination of clinical signs and electroencephalogram (EEG) and kept the duration of treatment as short as possible after abolishing convulsion..

Results: In the neonates 11 died. Of the surviving infants, 44 were treated for two to 21 days (average 7.30±2.55 days), and four continued with anticonvulsive treatment. Follow up data were a age of 12 months, three were lost to follow up. Of the 45 surviving infants, four (8.89%) had recurrence of convulsion during the first year of life. Two (4.88%) in the four infants with convulsion recurrence received early withdrawal of anticunvulsive treatment. Owing to the small number of infants with convulsion recurrence, the mortality was low (8.89%).

Conclusion: The results showed that there was low risk of convulsion recurrence after early withdrawal of anticonvulsive treatment in the neonatal period after abolishing convulsion.