FAMILIAL MARRIAGE AND ITS CONNECTION WITH CONGENITAL
ANOMALIES
S.A. Rahmani
Medical School,
Tabriz University of Medical Sciences, Iran
Because of
there is high rate of familial marriage (F.M) in IRAN, we decide to study
about to and its effect in congenital disorders such as blindness (B),
deafness (D) and Congenital heart diseases (CHD).
Work began with
providing a special questionnaire for B & F, and research began in B
& D schools, for the CHD patients that have had a open heart surgery,
data extract from hospital records of them.
In control
group from 416 family that was selected Randomized., 91 family about 21.87
percent had F.M.
From 424
patient about 58 percent was resulted from F.M and about 16/5 percent had
positive family histories, in blindness patients, from 93 B, about 54
percent of patient had F.M and 44 percent had positive family histories. in
CHD, from 75 patient about 30 percent had F.M.
Finally the X 2
test and odds ratio was done, in comparison of D & B with F.M and
positive history and control group, result was significance (P<0.001)
and odds ratio for B= 4/22 & D = 4/93.
In CHD, the X 2
test is done and F.M effect in CHD was positive (P<0.001) and also odds
ratio for this study was 1.6.